Nobivac® DHPPi

The combination 5 in 1 vaccine against canine distemper virus (CDV), canine adenovirus type 1 (CAV1) and 2 (CAV2), canine parvovirus (CPV) and canine parainfluenza virus (Cpi). The only vaccine with the 10 weeks final vaccination claim.

Description
Nobivac DHPPi is a combined live vaccine against canine distemper virus (CDV), canine adeno virus type 1 (CAV1) and 2 (CAV2), canine parvo virus (CPV) and canine para-influenza virus (CPi). In the USA Nobivac DHPPi is sold as Progard 5 (Progard 7 in combination with Nobivac Lepto, and Progard 8 in combination with Nobivac LC). Nobivac DHPPi has a duration of immunity of 2 years for the CDV, CAV and CPV components and 1 year for the CPi component. With Nobivac DHPPi, the final vaccination of puppies can be carried out at an age as young as 10-12 weeks allowing for early socialisation and prevention of behavioural problems.

Composition
Each dose contains ≥ 107 TCID50 of the attenuated strain C154 of canine parvo virus, ≥ 104 TCID50 of the attenuated strain Onderstepoort of canine distemper virus, ≥ 104 TCID50 of the attenuated strain Manhattan LPV3 of canine adeno virus type 2 and ≥ 105,5 TCID50 of the attenuated strain Cornell of canine para-influenza virus.

Formulation
Freeze dried plug with accompanying diluent.

Indications
Vaccination against CDV, CAV2, CPV and CPi. Besides providing protection against CAV2 disease entities such as respiratory tract infections the vaccine also protects against infectious canine hepatitis (ICH) caused by CAV1.

Vaccination
Nobivac DHPPi is indicated to complete the basic vaccination schedule of puppies, and for annual or bi-annual revaccination. Vaccination with Nobivac DHPPi however is part of a comprehensive vaccination programme. Several alternatives exist. (See Vaccination programme for dogs).

Method of administration
Reconstitute one vial of Nobivac DHPPi in one vial of Nobivac Solvens, Nobivac Lepto, Nobivac Rabies, Nobivac Corona, Nobivac LC or Nobivac RL, and inject subcutaneously.

Presentation
Boxes containing 5 or 25 vials of Nobivac DHPPi in combination with an equal number of vials with Nobivac Solvens, Nobilis L, Nobivac LC or Nobivac LR, or boxes containing 10 or 50 vials of Nobivac DHPPi

Storage
Store at a temperature of 2-8°C.

Further information
Nobivac DHPPi is safe in pregnant bitches.

Precautions
Occasionally a mild, anaphylactic-type hypersensitivity reaction may occur after vaccination. This type of reaction can occur after the injection of any foreign protein and is, in most cases, self-limiting.